It appeared that Juliette joined Mittelos in Miami. Is it a bad assumption to think that is where they boarded the sub? If that's the case how could the island be in the south pacific? In order to go from Miami to the S.Pacific it would have to travel all the way around S. America. I doubt they took it through the Panama Canal. I guess it's possible that they boarded a plane in Miami and flew to a west coast location where the sub was. With Juliette being drugged I guess anything could have happened. I just thought it was weird.

If they took a plane it couldn't have been a commercial flight because it would look a little weird traveling with a passed out woman over your shoulder.